Kidney tumor in a von hippel-lindau (VHL) patient with intensely increased activity on 68ga-DOTA-TATE PET/CT
Clinical Nuclear Medicine, 41(12), 970–971
Abstract
Renal and pancreatic cysts and tumors are the most common visceral manifestations of von Hippel-Lindau (VHL) disease, a heritable multisystem cancer syndrome characterized by development of a variety of malignant and benign tumors. We report a case of a VHL patient with multiple renal cystic and complex cystic/solid lesions. The patient underwent Ga-DOTA-TATE-PET/CT showing intensely increased activity by a solid lesion which demonstrated enhancement on both CT and MRI scans, raising high suspicion for malignancy. The presented case indicates application of SSTR-imaging using Ga-DOTA-conjugated peptides in VHL-patients and emphasizes the need for cautious interpretation of renal parenchyma Ga-DOTATATE activity.
Abstract sourceThis 2016 case report describes intense 68Ga-DOTA-TATE uptake in a solid renal lesion in a patient with von Hippel-Lindau disease, highlighting the need for cautious interpretation of renal tracer activity.
Summary
This case report describes a patient with von Hippel-Lindau (VHL) disease and multiple renal lesions. A solid lesion showed intense activity on 68Ga-DOTA-TATE PET/CT and enhancement on CT and MRI, raising suspicion of malignancy. The authors emphasize cautious interpretation of renal parenchymal uptake. The report concerns a single case; the lesion’s imaging findings raised suspicion but do not establish a general diagnostic performance or clinical readiness for this imaging approach. Read the full article.
Cite this work
Georgios Z. Papadakis; Corina Millo; Samira M. Sadowski; Ulas Bagci; Nicholas J. Patronas (2016). Kidney tumor in a von hippel-lindau (VHL) patient with intensely increased activity on 68ga-DOTA-TATE PET/CT. Clinical Nuclear Medicine, 41(12), 970–971 https://doi.org/10.1097/RLU.0000000000001393
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