Schmorl’s nodes can cause increased 68ga-DOTA-TATE activity on PET/CT, mimicking metastasis in patients with neuroendocrine malignancy

Georgios Z. Papadakis; Corina Millo; Ulas Bagci; Samira M. Sadowski; Constantine A. Stratakis

Clinical Nuclear Medicine, 41(3):249–250

Abstract

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This 2016 case report describes focal 68Ga-DOTA-TATE uptake associated with a Schmorl’s node, a benign vertebral endplate abnormality, that could be mistaken for bone metastasis in a patient with a history of neuroendocrine tumor.

Summary

In this case report, imaging of a patient with a history of neuroendocrine tumor showed increased focal 68Ga-DOTA-TATE uptake in a vertebra, raising concern for bone metastasis. CT findings were characteristic of a Schmorl’s node, in which disc material protrudes through the vertebral endplate into the adjacent vertebral body. The authors note that this benign finding should be considered when interpreting focal skeletal uptake on 68Ga-DOTA-TATE PET/CT. Read the published article.

Cite this work

Georgios Z. Papadakis; Corina Millo; Ulas Bagci; Samira M. Sadowski; Constantine A. Stratakis (2016). Schmorl’s nodes can cause increased 68ga-DOTA-TATE activity on PET/CT, mimicking metastasis in patients with neuroendocrine malignancy. Clinical Nuclear Medicine, 41(3):249–250 https://doi.org/10.1097/RLU.0000000000001065

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