Talc pleurodesis with intense 18F-FDG activity but no 68ga-DOTA-TATE activity on PET/CT
Clinical Nuclear Medicine, 40(10), 819–820
Abstract
Talc pleurodesis (TP) is a technique, widely employed in the management of patients with persistent pleural effusions or pneumothoraces not amenable to other treatment options. It is well documented that talc deposits produce areas of highly increased F-FDG uptake, because of talc-induced inflammation. We present a case of a patient with history of TP who was evaluated with both F-FDG and Ga-DOTA-TATE. The hypermetabolic area seen on F-FDG-PET-CT in the region of talc placement showed no uptake by Ga-DOTA-TATE, suggesting the potential role of Ga-DOTA-TATE-PET-CT in elucidating F-FDG-postitive lesions in patients with history of both neuroendocrine malignancy and TP.
Abstract sourceThis 2015 case report describes PET/CT findings at a site of talc pleurodesis: intense 18F-FDG activity without 68Ga-DOTA-TATE uptake. The authors discuss the potential relevance of this difference when interpreting imaging in a patient with neuroendocrine malignancy and prior talc pleurodesis.
Summary
The authors report PET/CT findings in a patient with a history of talc pleurodesis. Imaging showed intense 18F-FDG activity at the talc placement site, while 68Ga-DOTA-TATE PET/CT showed no uptake in the corresponding area. The report discusses the potential role of 68Ga-DOTA-TATE PET/CT in evaluating FDG-avid findings in patients with both neuroendocrine malignancy and prior talc pleurodesis. This is a case report; the observation does not establish diagnostic performance or clinical readiness. Read the article.
Cite this work
Georgios Z Papadakis; Corina Millo; Ulas Bagci; Nicholas J Patronas; Constantine A Stratakis (2015). Talc pleurodesis with intense 18F-FDG activity but no 68ga-DOTA-TATE activity on PET/CT. Clinical Nuclear Medicine, 40(10), 819–820 https://doi.org/10.1097/RLU.0000000000000807
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